Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 17/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730702 | 0.83 | KMT2A (0.48) | MMP13TSHRKMT2ASRCKDM4E | |
| Hydrochloric Acid SCHEMBL11732858 | 0.78 | SRC (0.48) | MMP13TSHRMEN1POLBKMT2A | |
| SCHEMBL11732811 | 0.78 | MMP13 (0.43) | MMP13MEN1KMT2ASRC | |
| SCHEMBL11734775 | 0.77 | SRC (0.53) | MMP13TSHRMEN1POLBKMT2A | |
| SCHEMBL11552437 | 0.77 | SRC (0.53) | MMP13TSHRMEN1POLBKMT2A | |
| SCHEMBL11734875 | 0.76 | PGK1 (0.45) | TSHRMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL11551636 | 0.75 | SRC (0.56) | TSHRMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL11548016 | 0.75 | ALDH1A1 (0.45) | MMP13TSHRMEN1POLBKMT2A | |
| SCHEMBL11553496 | 0.74 | SRC (0.55) | TSHRMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL11735105 | 0.74 | NPC1 (0.47) | TSHRMEN1POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011324-A | Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents | PFIZER INC. (US) | 1977-03-08 | — | — | US | disclosed |