Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 14/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP10 | P09238 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730702 | 0.90 | KMT2A (0.48) | MMP13SRCKMT2A | |
| SCHEMBL11727542 | 0.87 | MMP13 (0.50) | MMP13MEN1KMT2AMMP2MMP10 | |
| SCHEMBL11734875 | 0.78 | PGK1 (0.45) | SRCMEN1KMT2A | |
| SCHEMBL11732835 | 0.78 | MMP13 (0.43) | MMP13SRCMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11732858 | 0.77 | SRC (0.48) | MMP13SRCMEN1KMT2A | |
| SCHEMBL11734775 | 0.75 | SRC (0.53) | MMP13SRCMEN1KMT2A | |
| SCHEMBL11552437 | 0.75 | SRC (0.53) | MMP13SRCMEN1KMT2A | |
| SCHEMBL11729280 | 0.74 | MAPT (0.43) | MMP13MMP2MMP10MMP8 | |
| SCHEMBL11548016 | 0.74 | ALDH1A1 (0.45) | MMP13SRCMEN1KMT2A | |
| SCHEMBL11553496 | 0.73 | SRC (0.55) | SRCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011324-A | Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents | PFIZER INC. (US) | 1977-03-08 | — | — | US | disclosed |