Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGFR | P43088 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731240 | 0.92 | ALDH1A1 (0.43) | TBXA2RALDH1A1FABP4PTGER1PTGFR | |
| SCHEMBL11732372 | 0.88 | FAAH (0.36) | — | |
| SCHEMBL11732610 | 0.87 | GRM2 (0.34) | TBXA2RALDH1A1PTGER1PTGFRPTGER3 | |
| SCHEMBL11729918 | 0.86 | LMNA (0.44) | TBXA2RALDH1A1FABP4PTGER1PTGFR | |
| SCHEMBL11730097 | 0.85 | TBXA2R (0.51) | TBXA2RALDH1A1FABP4PTGER1PTGFR | |
| SCHEMBL11733330 | 0.84 | CYP1A2 (0.47) | TBXA2RALDH1A1FABP4PTGER1PTGFR | |
| SCHEMBL11850224 | 0.82 | PTGFR (0.57) | TBXA2RALDH1A1FABP4PTGER1PTGFR | |
| SCHEMBL11735554 | 0.81 | PTGFR (0.45) | TBXA2RPTGER1PTGFRPTGER3LMNA | |
| SCHEMBL11726284 | 0.81 | TBXA2R (0.45) | TBXA2RALDH1A1FABP4PTGER1PTGFR | |
| Water SCHEMBL11730250 | 0.81 | PTGFR (0.56) | TBXA2RALDH1A1FABP4PTGER1PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |