Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859408 | 0.80 | OPRD1 (0.47) | PRCPSIGMAR1 | |
| SCHEMBL11870243 | 0.76 | OPRD1 (0.52) | PRCPSIGMAR1 | |
| SCHEMBL14650822 | 0.73 | PRCP (0.64) | PRCPSIGMAR1 | |
| SCHEMBL11870073 | 0.70 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL12175477 | 0.69 | PRCP (0.62) | PRCPSIGMAR1 | |
| SCHEMBL12175514 | 0.69 | PRCP (0.72) | PRCPSIGMAR1 | |
| SCHEMBL12175475 | 0.69 | PRCP (0.61) | PRCPSIGMAR1 | |
| SCHEMBL14650830 | 0.66 | PRCP (0.70) | PRCP | |
| SCHEMBL15894615 | 0.66 | PRCP (0.59) | PRCPSIGMAR1 | |
| SCHEMBL15894614 | 0.66 | PRCP (0.73) | PRCPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031224-A | 1,3-Dihydro-heteroarylspiro (isobenzofuran)s | AMERICAN HOECHST CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |