Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870243 | 0.93 | OPRD1 (0.52) | OPRD1KCNH2PRCPSIGMAR1OPRM1 | |
| SCHEMBL11863710 | 0.84 | SIGMAR1 (0.60) | OPRD1SIGMAR1OPRM1OPRK1 | |
| SCHEMBL14650822 | 0.82 | PRCP (0.64) | PRCPSIGMAR1 | |
| SCHEMBL11778403 | 0.82 | OPRD1 (0.47) | OPRD1KCNH2PRCPSIGMAR1OPRM1 | |
| SCHEMBL11849041 | 0.81 | OPRD1 (0.46) | OPRD1KCNH2PRCPSIGMAR1OPRM1 | |
| SCHEMBL11733338 | 0.80 | PRCP (0.45) | PRCPSIGMAR1 | |
| SCHEMBL11858736 | 0.80 | OPRD1 (0.54) | OPRD1KCNH2PRCPSIGMAR1OPRM1 | |
| SCHEMBL11684907 | 0.79 | SIGMAR1 (0.70) | OPRD1PRCPSIGMAR1OPRM1OPRK1 | |
| SCHEMBL12175477 | 0.78 | PRCP (0.62) | PRCPSIGMAR1 | |
| SCHEMBL11851978 | 0.78 | KCNH2 (0.52) | OPRD1KCNH2PRCPSIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | claimed |
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |