Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536276 | 0.80 | S100A4 (0.44) | POLBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4572616 | 0.74 | — | — | |
| SCHEMBL30956071 | 0.73 | CA2 (0.41) | CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL29700326 | 0.72 | POLB (0.61) | POLBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6916799 | 0.72 | POLB (0.61) | POLBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10679407 | 0.71 | POLB (0.64) | POLBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2959541 | 0.70 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1GAAS100A4HSD17B10 | |
| SCHEMBL22531901 | 0.70 | POLB (0.49) | POLBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9025993 | 0.69 | POLB (0.52) | POLBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11738688 | 0.68 | ALDH1A1 (0.34) | POLBSMN1; SMN2ALDH1A1LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041186-A | ADJUVANTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-4007287-A | Flavoring with (allyl)(2-methyl-3-furyl) sulfide | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1977-02-08 | — | — | US | disclosed |
| US-3988510-A | 3-Furyl sulfides and foodstuff flavor compositions comprising same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-10-26 | — | — | US | disclosed |