SCHEMBL11736412

SCHEMBL11736412

O=c1cc(CCBr)[nH]c(=S)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LPO P22079 2/20 0.67
▸ CYP2C19 P33261 2/20 0.67
▸ TAS2R38 P59533 2/20 0.67
▸ MPO P05164 2/20 0.67
▸ TPO P07202 1/20 0.67
▸ TSHR P16473 1/20 0.67
▸ KMT2A Q03164 1/20 0.61
▸ MAPT P10636 1/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.51
▸ CYB5R3 P00387 3/20 0.47
▸ ALDH1A1 P00352 3/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ PTGS1 P23219 1/20 0.45
▸ BAZ2B Q9UIF8 1/20 0.45
▸ GPR84 Q9NQS5 5/20 0.37
▸ TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylthiouracil SCHEMBL5493716 0.80 LPO (1.00) LPOCYP2C19TAS2R38MPOTPO
Propylthiouracil SCHEMBL41239 0.80 LPO (1.00) LPOCYP2C19TAS2R38MPOTPO
SCHEMBL11741161 0.80 CYP2C19 (0.67) LPOCYP2C19TAS2R38MPOTPO
SCHEMBL23160962 0.75 LPO (0.71) LPOCYP2C19TAS2R38MPOTPO
SCHEMBL29948466 0.74 KMT2A (0.97) LPOCYP2C19TAS2R38MPOTPO
Propylthiouracil SCHEMBL13723721 0.73 LPO (0.83) LPOCYP2C19TAS2R38MPOTPO
SCHEMBL10489669 0.71 LPO (0.55) LPOCYP2C19TAS2R38MPOTPO
SCHEMBL21328426 0.69 TSHR (0.53) LPOCYP2C19TAS2R38MPOTPO
Propylthiouracil SCHEMBL20771755 0.69 LPO (0.73) LPOCYP2C19TAS2R38MPOTPO
SCHEMBL11582733 0.69 KMT2A (0.82) LPOCYP2C19TAS2R38MPOTPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841062-B2 Positive working photosensitive material AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2014-09-23 — — US claimed
US-20140154624-A1 POSITIVE WORKING PHOTOSENSITIVE MATERIAL AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2014-06-05 — — US claimed
US-4002479-A ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 — — US claimed
US-12619149-B2 DNQ-free chemically amplified resist composition MERCK PATENT GMBH (DE) 2026-05-05 — — US disclosed
US-12393115-B2 Positive working photosensitive material MERCK PATENT GMBH (DE) 2025-08-19 — — US disclosed
US-20250244669-A1 COMPOSITIONS AND METHODS OF IMPROVING METAL STRUCTURE FABRICATION BY WET CHEMICAL ETCH EMD PERFORMANCE MATERIALS CORP. 2025-07-31 — — US disclosed
US-12360453-B2 PAG-free positive chemically amplified resist composition and methods of using the same MERCK PATENT GMBH (DE) 2025-07-15 — — US disclosed
CN-114651212-B Positive photosensitive material 默克专利股份有限公司 2025-05-02 — — CN disclosed
EP-4433873-A2 COMPOSITIONS AND METHODS FOR IMPROVING METAL STRUCTURE FABRICATION BY WET CHEMICAL ETCH Merck Patent GmbH (DE) 2024-09-25 — — EP disclosed
CN-112654928-B Positive photosensitive material 默克专利股份有限公司 2024-09-24 — — CN disclosed
CN-118642327-A Chemically amplified positive photosensitive composition, method for producing molded substrate with mold, and method for producing plated molded article 东京应化工业株式会社 2024-09-13 — — CN disclosed
EP-3446180-B1 POSITIVE WORKING PHOTOSENSITIVE MATERIAL AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) 2020-04-01 — — EP disclosed
EP-2929397-B1 POSITIVE WORKING PHOTOSENSITIVE MATERIAL AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) 2020-03-18 — — EP disclosed
US-20190278178-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING SUBSTRATE WITH TEMPLATE, AND METHOD FOR MANUFACTURING PLATED ARTICLE TOKYO INSTITUTE OF TECHNOLOGY (JP) 2019-09-12 — — US disclosed
EP-2929397-A2 POSITIVE WORKING PHOTOSENSITIVE MATERIAL AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2015-10-14 — — EP disclosed
CN-104781731-A Positive working photosensitive material AZ ELECTRONIC MATERIALS LUXEMBOURG SARL 2015-07-15 — — CN disclosed
US-8841062-B2 Positive working photosensitive material AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2014-09-23 — — US disclosed
WO-2014086846-A2 POSITIVE WORKING PHOTOSENSITIVE MATERIAL AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2014-06-12 — — WO disclosed
US-20140154624-A1 POSITIVE WORKING PHOTOSENSITIVE MATERIAL AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2014-06-05 — — US disclosed
US-4002479-A ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12619149-B2 DNQ-free chemically amplified resist composition POLQ, RECQL, RPA1 LPO 3512/4885CYP2C19 3727/4885TAS2R38 1006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback