Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | TPO | P07202 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYB5R3 | P00387 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662039 | 0.80 | GPR84 (0.46) | TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11121299 | 0.76 | XDH (0.35) | TSHRMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL28714131 | 0.74 | GPR84 (0.50) | — | |
| SCHEMBL23160962 | 0.74 | LPO (0.71) | LPOCYP2C19TAS2R38MPOTPO | |
| SCHEMBL8516381 | 0.71 | — | — | |
| SCHEMBL11741161 | 0.71 | CYP2C19 (0.67) | LPOCYP2C19TAS2R38MPOTPO | |
| Propylthiouracil SCHEMBL5493716 | 0.71 | LPO (1.00) | LPOCYP2C19TAS2R38MPOTPO | |
| Propylthiouracil SCHEMBL41239 | 0.71 | LPO (1.00) | LPOCYP2C19TAS2R38MPOTPO | |
| SCHEMBL21328426 | 0.68 | TSHR (0.53) | LPOCYP2C19TAS2R38MPOTPO | |
| SCHEMBL29955654 | 0.67 | SMN1; SMN2 (0.50) | LPOCYP2C19TAS2R38MPOTPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080160445-A1 | Planographic printing plate material, and method of preparing planographic printing plate employing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080160445-A1 | Planographic printing plate material, and method of preparing planographic printing plate employing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-4857149-A | SIZING COMPOUND CONTAINING BOTH HYDROPHILIC AND HYDROPHOBIC PO RTIONS; ALKOYL OR ALKENOYL HYDROZAMIC ACID | WEYERHAEUSER COMPANY (US) | 1989-08-15 | — | — | US | disclosed |
| WO-1988002047-A1 | METHOD AND PRODUCTS FOR SIZING PAPER AND SIMILAR MATERIALS | WEYERHAEUSER COMPANY (US) | 1988-03-24 | — | — | WO | disclosed |
| US-3950339-A | SUBSTITUTED-2-(PYRIMIDINYLTHIO)ACETAMIDOXIMES AND ACETONITRILES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |