SCHEMBL923353

SCHEMBL923353

CCc1ccc(Oc2cccc(CN)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.58
MAOB P27338 3/20 0.51
ALDH1A1 P00352 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 1/20 0.44
MITF O75030 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
GFER P55789 1/20 0.44
KMT2A Q03164 1/20 0.44
NLRP1 Q9C000 1/20 0.44
NOD2 Q9HC29 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919982 0.95 ST14 (0.60) ST14MAOBALDH1A1SMN1; SMN2KDM4E
SCHEMBL920952 0.91 ST14 (0.48) ST14MAOBALDH1A1SMN1; SMN2KDM4E
SCHEMBL11736722 0.89 ALDH1A1 (0.53) ST14ALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL920620 0.87 ST14 (0.68) ST14MAOBSMN1; SMN2LOXL2TAAR1
SCHEMBL921397 0.87 ST14 (0.55) ST14MAOBALDH1A1SMN1; SMN2KDM4E
SCHEMBL4949955 0.85 ST14 (0.58) ST14MAOBALDH1A1SMN1; SMN2MEN1
SCHEMBL924115 0.85 LTA4H (0.59) ST14MAOBTDP1LOXL2
SCHEMBL920590 0.84 ST14 (0.55) ST14MAOBALDH1A1SMN1; SMN2KDM4E
SCHEMBL921289 0.84 MAOB (0.61) ST14MAOBALDH1A1SMN1; SMN2KDM4E
SCHEMBL5597563 0.84 ST14 (0.51) ST14MAOBALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885MAOB 3730/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.