Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415678 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL11736722 | 0.89 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL9502164 | 0.87 | FDFT1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL13857071 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL8549352 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL9488681 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL30358275 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL919982 | 0.84 | ST14 (0.60) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL8241107 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 | |
| SCHEMBL5407250 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4ESMN1; SMN2HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4612323-A | Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |