Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 5/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735068 | 0.84 | THRB (0.45) | TP53ALDH1A1THRBLMNAPOLB | |
| SCHEMBL11594612 | 0.75 | ENPP2 (0.38) | AKR1B1CCR1CCR2LMNA | |
| SCHEMBL11664985 | 0.75 | LMNA (0.39) | TP53AKR1B1METLMNA | |
| SCHEMBL11644929 | 0.72 | LMNA (0.36) | TP53AKR1B1THRBLMNAGAA | |
| SCHEMBL11731688 | 0.71 | MAPK14 (0.50) | TP53ALDH1A1THRBLMNA | |
| SCHEMBL11743457 | 0.70 | KMT2A (0.47) | TP53ALDH1A1THRBLMNA | |
| SCHEMBL2543072 | 0.68 | ALDH1A1 (0.55) | ALDH1A1METTHRBGAA | |
| SCHEMBL11713443 | 0.67 | GRM7 (0.43) | CCR1CCR2 | |
| SCHEMBL29349011 | 0.66 | HSD17B10 (0.42) | ALDH1A1CCR1CCR2HSD17B10GAA | |
| SCHEMBL6329653 | 0.65 | PARP1 (0.43) | ALDH1A1CCR1CCR2HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033751-A | 2-(Substituted-phenyl)-hexahydro- and tetrahydro-3-(2H)-cinnolinones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-07-05 | — | — | US | disclosed |