Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731184 | 0.89 | HTR1A (0.37) | HTR6 | |
| SCHEMBL11738762 | 0.88 | HTR6 (0.36) | HTR6METAP1CYP2D6HRH1KCNH2 | |
| SCHEMBL11647423 | 0.86 | HTR6 (0.45) | HTR6METAP1 | |
| SCHEMBL11737012 | 0.86 | DRD3 (0.35) | HTR6 | |
| SCHEMBL11736091 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL7436995 | 0.83 | HTR6 (0.46) | HTR6 | |
| SCHEMBL26639689 | 0.83 | HTR6 (0.46) | HTR6 | |
| SCHEMBL26646007 | 0.83 | HTR6 (0.46) | HTR6 | |
| SCHEMBL11735864 | 0.81 | METAP1 (0.35) | HTR6METAP1CYP2D6HRH1KCNH2 | |
| SCHEMBL11732657 | 0.81 | SIGMAR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014884-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |