Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363631 | 0.76 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL29705809 | 0.76 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL12175569 | 0.74 | PRCP (0.56) | SIGMAR1OPRD1KCNH2PRCP | |
| Bromide SCHEMBL11735141 | 0.73 | OPRD1 (0.43) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL30508374 | 0.72 | SIGMAR1 (0.46) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11686154 | 0.72 | PRCP (0.43) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11782034 | 0.72 | SIGMAR1 (0.46) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11870107 | 0.72 | SIGMAR1 (0.43) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11738746 | 0.71 | SIGMAR1 (0.42) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL12175500 | 0.71 | PRCP (0.54) | SIGMAR1OPRD1KCNH2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031224-A | 1,3-Dihydro-heteroarylspiro (isobenzofuran)s | AMERICAN HOECHST CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |