Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | PRCP | P42785 | 6/20 | 0.36 |
| ▸ | ESRRB | O95718 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESRRG | P62508 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363631 | 0.88 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL29705809 | 0.88 | OPRD1 (0.50) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11686154 | 0.86 | PRCP (0.43) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL30508374 | 0.86 | SIGMAR1 (0.46) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11782034 | 0.86 | SIGMAR1 (0.46) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11782410 | 0.84 | DRD1 (0.44) | SIGMAR1OPRD1KCNH2ESR1 | |
| SCHEMBL11783954 | 0.84 | DRD2 (0.41) | SIGMAR1OPRD1KCNH2 | |
| SCHEMBL11853705 | 0.83 | SIGMAR1 (0.49) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11858464 | 0.81 | OPRD1 (0.47) | SIGMAR1OPRD1KCNH2PRCP | |
| SCHEMBL11781458 | 0.80 | OPRD1 (0.46) | SIGMAR1OPRD1KCNH2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | claimed |