Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735265 | 0.91 | SIGMAR1 (0.50) | ACHESIGMAR1 | |
| SCHEMBL11739462 | 0.90 | ACHE (0.52) | ACHEBCHESIGMAR1 | |
| SCHEMBL11734383 | 0.90 | ACHE (0.49) | ACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL11732327 | 0.90 | ACHE (0.49) | ACHEBCHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL11737929 | 0.89 | ACHE (0.48) | ACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL11735355 | 0.86 | OPRM1 (0.56) | ACHEBCHEOPRM1OPRL1SIGMAR1 | |
| SCHEMBL11729808 | 0.85 | ACHE (0.48) | ACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL11735592 | 0.85 | ACHE (0.48) | ACHEBCHE | |
| SCHEMBL11731442 | 0.85 | KMT2A (0.50) | ACHEOPRM1OPRL1SIGMAR1 | |
| SCHEMBL11735116 | 0.84 | ACHE (0.51) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016281-A | Tetralone and indanone compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-04-05 | — | — | US | disclosed |