Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572861 | 0.84 | MAPT (0.55) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL27903009 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL11739281 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL11273478 | 0.78 | DRD2 (0.46) | ALDH1A1MAPK1GAAALOX15KMT2A | |
| SCHEMBL3194473 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL1815632 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMAPK1KMT2A | |
| SCHEMBL6226347 | 0.74 | KDM1A (0.49) | ALDH1A1HPGDHSD17B10KDM4ETP53 | |
| SCHEMBL27638247 | 0.74 | CA12 (0.47) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| Urea SCHEMBL28788053 | 0.73 | ALDH1A1 (0.67) | ALDH1A1HPGDHSD17B10KDM4EPLAU | |
| SCHEMBL4050173 | 0.73 | MAPT (0.50) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | ALDH1A1 14/4885HPGD 628/4885HSD17B10 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.