Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204976 | 0.98 | TEAD4 (0.42) | HTR2ASLC6A4KCNH2TEAD4IDH1 | |
| SCHEMBL28302613 | 0.87 | L3MBTL1 (0.50) | IDH1ALDH1A1TDP1L3MBTL1CNR2 | |
| SCHEMBL4624112 | 0.86 | PYCR1 (0.42) | ALDH1A1TDP1KDM4ESMN1; SMN2CNR2 | |
| SCHEMBL17771266 | 0.82 | PDE3B (0.40) | HTR2ASLC6A4KCNH2ALDH1A1KDM4E | |
| SCHEMBL1539299 | 0.80 | ACHE (0.48) | MAPTL3MBTL1CNR2 | |
| SCHEMBL14407100 | 0.79 | PYCR1 (0.38) | ALDH1A1TDP1KDM4EPYCR1 | |
| SCHEMBL10950441 | 0.79 | MAP2K4 (0.41) | ALDH1A1TDP1KDM4EPYCR1 | |
| SCHEMBL7566966 | 0.79 | ESR1 (0.48) | IDH1ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL7952150 | 0.79 | L3MBTL1 (0.35) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9234531 | 0.79 | LTA4H (0.49) | HTR2ASLC6A4IDH1MAPTSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |