Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742667 | 0.86 | NPSR1 (0.58) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL11720785 | 0.81 | KDM4E (0.44) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10694441 | 0.80 | KDM4E (0.65) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1887466 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL436153 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL27796465 | 0.79 | ALDH1A1 (0.68) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9866412 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL16042060 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL521212 | 0.79 | MAPT (0.97) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30016904 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029687-A | HERBICIDES | CIBA-GEIGY AG (CH) | 1977-06-14 | — | — | US | disclosed |
| US-3951641-A | Use of N-(4-isopropoxy-3-chlorophenyl)-N'-methyl-N'-methoxyurea for control of weeds in maize cultures | CIBA-GEIGY AG (CH) | 1976-04-20 | — | — | US | disclosed |