Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 5/20 | 0.62 |
| ▸ | MMP9 | P14780 | 5/20 | 0.62 |
| ▸ | MMP8 | P22894 | 5/20 | 0.62 |
| ▸ | MMP13 | P45452 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.60 |
| ▸ | RELA | Q04206 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745692 | 0.85 | CHEK2 (0.60) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL3183363 | 0.85 | NPBWR1 (0.63) | RHEBMMP2MMP9MMP8MMP13 | |
| SCHEMBL5219206 | 0.85 | NPBWR1 (0.77) | RHEBMMP2MMP9MMP8MMP13 | |
| SCHEMBL11746348 | 0.84 | CHEK2 (0.53) | RHEBNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL28483088 | 0.83 | NPC1 (0.71) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL8610747 | 0.82 | NPBWR1 (0.60) | RHEBMMP2MMP9MMP8MMP13 | |
| SCHEMBL19995192 | 0.82 | NPBWR1 (0.69) | RHEBMMP2MMP9MMP8MMP13 | |
| SCHEMBL25318263 | 0.81 | KDM4E (0.75) | RHEBMMP2MMP9MMP8MMP13 | |
| SCHEMBL20982713 | 0.81 | KDM4E (0.75) | RHEBMMP2MMP9MMP8MMP13 | |
| SCHEMBL29906102 | 0.81 | KDM4E (0.75) | RHEBMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001268-A | SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-04 | — | — | US | disclosed |