Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 9/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | MMP8 | P22894 | 2/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743141 | 0.85 | RHEB (0.67) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL28475608 | 0.85 | RAB9A (0.68) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL11746348 | 0.84 | CHEK2 (0.53) | CHEK2NPBWR1NPC1MAPTRAB9A | |
| SCHEMBL5221558 | 0.83 | NPBWR1 (0.80) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL3195153 | 0.83 | CHEK2 (0.65) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL5217725 | 0.81 | CHEK2 (0.87) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL5217712 | 0.81 | CHEK2 (0.71) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL20982607 | 0.79 | CHEK2 (0.63) | CHEK2MMP2MMP9MMP8MMP13 | |
| SCHEMBL28475614 | 0.79 | NPC1 (0.56) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL28483088 | 0.79 | NPC1 (0.71) | CHEK2MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001268-A | SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-04 | — | — | US | disclosed |