Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13589494 | 0.82 | PTGS2 (0.45) | — | |
| SCHEMBL2626589 | 0.81 | PNMT (0.46) | SMN1; SMN2GAAALDH1A1CA12CA1 | |
| SCHEMBL2301965 | 0.80 | ALDH1A1 (0.60) | GAAALDH1A1CA12CA1CA2 | |
| SCHEMBL11751048 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2299887 | 0.80 | HTR6 (0.56) | GAAALDH1A1CA12CA1CA2 | |
| SCHEMBL2301942 | 0.79 | MAPT (0.54) | GAAALDH1A1LMNAHTTMEN1 | |
| SCHEMBL2236663 | 0.79 | SCN9A (0.40) | SMN1; SMN2ALDH1A1CA1CA2CA4 | |
| SCHEMBL2300518 | 0.79 | MAPT (0.61) | SMN1; SMN2ALDH1A1CA1CA2LMNA | |
| SCHEMBL14119601 | 0.78 | KMT2A (0.67) | SMN1; SMN2GAAALDH1A1LMNAMEN1 | |
| SCHEMBL13588741 | 0.78 | EGFR (0.39) | ALDH1A1LMNASCN9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031229-A | SUBSTITUTED IMIDAZOLIDINONE-PENICILLANIC ACIDS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |