Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | JAK2 | O60674 | 9/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 3/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481432 | 0.82 | PDPK1 (1.00) | PDPK1KDM4EGAACYP3A4JAK2 | |
| SCHEMBL18878 | 0.82 | PDPK1 (1.00) | PDPK1KDM4EGAACYP3A4JAK2 | |
| SCHEMBL63099 | 0.78 | — | — | |
| Urea SCHEMBL2190330 | 0.77 | KDM4E (0.80) | PDPK1KDM4EGAACYP3A4JAK2 | |
| Hydrochloric Acid SCHEMBL9739519 | 0.75 | — | — | |
| Biphenyl SCHEMBL27604124 | 0.74 | PDPK1 (0.83) | PDPK1KDM4EGAACYP3A4JAK2 | |
| Bicarbonate SCHEMBL1573525 | 0.73 | KDM4E (0.80) | PDPK1KDM4EGAACYP3A4JAK2 | |
| Carbamic Acid SCHEMBL1857015 | 0.72 | KDM4E (0.77) | PDPK1KDM4EGAACYP3A4JAK2 | |
| Methylethylamine SCHEMBL15526348 | 0.71 | PDPK1 (0.69) | PDPK1KDM4EGAACYP3A4JAK2 | |
| SCHEMBL9042255 | 0.69 | KDM4E (0.73) | PDPK1KDM4EGAACYP3A4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017479-A | Cationic indazole-azo-5-amino pyrazole dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |