Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481432 | 0.85 | PDPK1 (1.00) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL18878 | 0.85 | PDPK1 (1.00) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| Urea SCHEMBL2190330 | 0.80 | KDM4E (0.80) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| Bicarbonate SCHEMBL1573525 | 0.80 | KDM4E (0.80) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| Carbamic Acid SCHEMBL1857015 | 0.78 | KDM4E (0.77) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL1023212 | 0.78 | CYP1A2 (0.63) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| Biphenyl SCHEMBL27604124 | 0.78 | PDPK1 (0.83) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL9041896 | 0.76 | CYP1A2 (0.61) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL3976004 | 0.76 | CYP1A2 (0.61) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL6480580 | 0.76 | CYP1A2 (1.00) | KDM4EGAAPDPK1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |