Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | IL2 | P60568 | 1/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12029822 | 0.93 | CA2 (0.62) | CA2CTSLPTPN1PRSS1PRSS2 | |
| SCHEMBL12029815 | 0.90 | CA2 (0.59) | CA2CTSLPTPN1PRSS1PRSS2 | |
| SCHEMBL11751332 | 0.90 | CTSL (0.60) | CA2CTSLPTPN1PRSS1PRSS2 | |
| SCHEMBL12029174 | 0.89 | ITGB3 (0.59) | CA2CTSLPTPN1ITGB3ITGA2B | |
| SCHEMBL12029323 | 0.89 | ITGB3 (0.59) | CA2CTSLPTPN1ITGB3ITGA2B | |
| SCHEMBL12029692 | 0.89 | ITGB3 (0.59) | CA2CTSLPTPN1ITGB3ITGA2B | |
| SCHEMBL10802837 | 0.88 | CTSL (0.71) | CA2CTSLPTPN1KMT2AITGB3 | |
| SCHEMBL11746806 | 0.88 | CTSL (0.71) | CA2CTSLPTPN1KMT2AITGB3 | |
| SCHEMBL12029785 | 0.88 | CTSL (0.58) | CA2CTSLPTPN1PRSS1PRSS2 | |
| SCHEMBL11744597 | 0.88 | CA2 (0.63) | CA2CTSLPTPN1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |