Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746806 | 0.88 | CTSL (0.71) | CA2PTPN1CTSLITGB3ITGA2B | |
| SCHEMBL10802837 | 0.88 | CTSL (0.71) | CA2PTPN1CTSLITGB3ITGA2B | |
| SCHEMBL11745003 | 0.88 | CA2 (0.69) | CA2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL11746310 | 0.88 | CTSL (0.57) | CA2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL11751332 | 0.88 | CTSL (0.60) | CA2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL12029785 | 0.85 | CTSL (0.58) | CA2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL11746757 | 0.85 | PRSS1 (0.58) | CA2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL11747136 | 0.83 | CA2 (0.67) | CA2PTPN1CTSLITGB3ITGA2B | |
| SCHEMBL11781869 | 0.83 | CTSL (0.48) | CA2PTPN1PRSS1PRSS2PRSS3 | |
| SCHEMBL13669574 | 0.83 | CA2 (0.70) | CA2PTPN1CTSLGPR132CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |