Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942450 | 0.98 | LMNA (0.41) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL8389044 | 0.95 | LMNA (0.41) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL1726278 | 0.92 | CYP2C19 (0.43) | LMNAMAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL5634948 | 0.81 | THRA (0.52) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL8390721 | 0.81 | THRA (0.52) | LMNAMAPTKMT2ACYP3A4MEN1 | |
| SCHEMBL11506132 | 0.80 | SMN1; SMN2 (0.38) | KMT2AMEN1CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL10940594 | 0.80 | ALDH1A1 (0.41) | MAPTKMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29193961 | 0.79 | CYP2C19 (0.41) | LMNAMAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL29193940 | 0.79 | CYP2C19 (0.41) | LMNAMAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL11428133 | 0.78 | ALDH1A1 (0.44) | LMNAMAPTKMT2ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4062829-A | PHOSPHORUS CONTAINING DICARBOXYLIC ACID ESTERS | EMERY INDUSTRIES, INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3994844-A | Vinyl halide resin compositions containing zinc organic phosphites | EMERY INDUSTRIES, INC. (US) | 1976-11-30 | — | — | US | disclosed |