Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTPRF | P10586 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546539 | 1.00 | ALDH3A1 (0.66) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL27971590 | 0.87 | MAPT (0.71) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL7512143 | 0.87 | ALDH3A1 (0.63) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL19921036 | 0.84 | ALDH3A1 (0.60) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL7095935 | 0.84 | ALDH1A1 (0.63) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL17199298 | 0.83 | ALDH3A1 (0.63) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL18582911 | 0.81 | ALDH3A1 (0.50) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL6378063 | 0.79 | HCAR3 (0.57) | ALDH3A1MAPTTSHR | |
| SCHEMBL6378059 | 0.79 | HCAR3 (0.57) | ALDH3A1MAPTTSHR | |
| SCHEMBL2060922 | 0.78 | ALDH1A1 (0.58) | ALDH3A1ALDH1A1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |