Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151033 | 0.89 | ALDH3A1 (0.56) | ALDH1A1MAPTMAPK1KMT2ATDP1 | |
| SCHEMBL29546539 | 0.84 | ALDH3A1 (0.66) | ALDH1A1MAPTMAPK1KMT2ATDP1 | |
| SCHEMBL11745238 | 0.84 | ALDH3A1 (0.66) | ALDH1A1MAPTMAPK1KMT2ATDP1 | |
| Formic Acid SCHEMBL28141504 | 0.82 | MAPT (0.50) | ALDH1A1MAPTMAPK1KMT2ATDP1 | |
| SCHEMBL28141500 | 0.81 | ALDH3A1 (0.46) | ALDH1A1MAPTMAPK1KMT2ATDP1 | |
| SCHEMBL7167935 | 0.79 | KAT2B (0.69) | ALDH1A1MAPTMAPK1KMT2ATDP1 | |
| SCHEMBL3202573 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KMT2ATDP1MEN1HTT | |
| SCHEMBL5108066 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL20592077 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1TSHRALDH3A1 | |
| SCHEMBL29389796 | 0.78 | NOX4 (0.57) | ALDH1A1MAPTMAPK1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086892-A1 | INTERLEUKIN 4 (IL4)-INDUCED GENE 1 INHIBITORS AND METHODS OF USE THEREOF | CALITHERA BIOSCIENCES, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |
| EP-0009800-B1 | 4-PHENYL-1,3-BENZODIAZEPINES, METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THE COMPOUNDS FOR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-23 | — | — | EP | disclosed |