Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | BLVRB | P30043 | 2/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745347 | 1.00 | PTGS2 (0.56) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| SCHEMBL11747967 | 0.86 | PHLPP2 (0.62) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| Potassium Ion SCHEMBL11747949 | 0.86 | PTGS2 (0.56) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| Potassium Ion SCHEMBL11747963 | 0.86 | PTGS2 (0.56) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| SCHEMBL5830402 | 0.85 | CA12 (0.65) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| SCHEMBL1647307 | 0.84 | CA2 (0.59) | PTGS2PTGS1ALDH1A1HSD17B10CA1 | |
| SCHEMBL7708973 | 0.83 | MEN1 (0.66) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| SCHEMBL7708976 | 0.83 | MEN1 (0.66) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| SCHEMBL10528243 | 0.83 | CA12 (0.67) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 | |
| SCHEMBL11743616 | 0.82 | PTGS1 (0.42) | PTGS2PTGS1PHLPP2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045429-A | 4-(4-Hydroxy- or acetoxy-3-carbomethoxyphenylazo)-benzenesulphonyl chloride | PHARMACIA AKTIEBOLAG (SW) | 1977-08-30 | — | — | US | claimed |
| US-4045429-A | 4-(4-Hydroxy- or acetoxy-3-carbomethoxyphenylazo)-benzenesulphonyl chloride | PHARMACIA AKTIEBOLAG (SW) | 1977-08-30 | — | — | US | disclosed |