Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745910 | 0.77 | F2 (0.40) | KMT2AMAPTF2TSHRGAA | |
| SCHEMBL20455579 | 0.75 | — | — | |
| SCHEMBL11748002 | 0.71 | MET (0.40) | TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL12081642 | 0.63 | ALDH1A1 (0.56) | KMT2AMAPTTSHRGAAALDH1A1 | |
| SCHEMBL6554973 | 0.61 | — | — | |
| SCHEMBL21066343 | 0.60 | GAA (0.35) | TSHRGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL17865708 | 0.60 | — | — | |
| SCHEMBL3681812 | 0.57 | TSHR (0.47) | KMT2AMAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL22181333 | 0.55 | — | — | |
| SCHEMBL308271 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006159-A | ACYL, VIRICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |