Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747582 | 0.88 | L3MBTL1 (0.37) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11747976 | 0.88 | PTGES (0.43) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11749644 | 0.86 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11742743 | 0.82 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11744427 | 0.81 | PTGES (0.42) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11749749 | 0.79 | MAPT (0.40) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL11864433 | 0.79 | PTGES (0.41) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11751925 | 0.78 | CACNA2D1 (0.47) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11749033 | 0.77 | PTGES (0.43) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL11743527 | 0.77 | MAPT (0.38) | ALDH1A1KDM4ELMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979516-A | Anti-inflammatory 3-amino-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | claimed |
| US-4008232-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3979516-A | Anti-inflammatory 3-amino-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3948894-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |