Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253687 | 0.83 | CA5A (0.48) | CA5AKMT2ALMNAPKMCYP19A1 | |
| SCHEMBL26162735 | 0.81 | ALDH1A1 (0.45) | CA5AKMT2AGSK3BMAPTL3MBTL1 | |
| SCHEMBL6155568 | 0.79 | MAOB (0.51) | KMT2ALMNAMAOBMAOA | |
| Ethylene Glycol SCHEMBL11272233 | 0.78 | LMNA (0.40) | KMT2ALMNAMAOBPOLBMAPT | |
| SCHEMBL25999808 | 0.78 | CA5A (0.48) | CA5AKMT2ALMNAPKMPOLB | |
| SCHEMBL18280564 | 0.78 | TPMT (0.48) | CA5AKMT2ACA1CA2LMNA | |
| SCHEMBL10498757 | 0.78 | RXRA (0.48) | CA5AKMT2ALMNAPKMPOLB | |
| SCHEMBL677142 | 0.76 | KMT2A (0.67) | KMT2ACA1CA2LMNAMAOB | |
| SCHEMBL20154209 | 0.76 | CA5A (0.46) | CA5AKMT2ALMNAMAOBPKM | |
| SCHEMBL8580812 | 0.75 | KMT2A (0.58) | CA5AKMT2AGSK3BLMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016194-A | CATALYTIC CARBONYLATION | TEXACO INC. (US) | 1977-04-05 | — | — | US | claimed |
| US-4016194-A | CATALYTIC CARBONYLATION | TEXACO INC. (US) | 1977-04-05 | — | — | US | disclosed |