Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687394 | 0.82 | KMT2A (0.67) | LMNAKMT2AMEN1POLB | |
| SCHEMBL11269894 | 0.81 | LMNA (0.60) | LMNAKMT2AMEN1CXCR2L3MBTL1 | |
| SCHEMBL11267633 | 0.75 | LMNA (0.69) | LMNAKMT2AMEN1CXCR2 | |
| SCHEMBL11687464 | 0.74 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2L3MBTL1ALOX5 | |
| SCHEMBL11490644 | 0.74 | LMNA (0.70) | LMNAKMT2AMEN1CXCR2SMN1; SMN2 | |
| SCHEMBL11273026 | 0.73 | LMNA (0.62) | LMNAKMT2AMEN1CXCR2 | |
| SCHEMBL11483687 | 0.72 | LMNA (0.92) | LMNAKMT2AMEN1CXCR2 | |
| SCHEMBL11484377 | 0.71 | KMT2A (0.57) | LMNAKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11401725 | 0.70 | HTT (0.64) | LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL11484122 | 0.70 | LMNA (0.69) | LMNAKMT2AMEN1CXCR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053484-A | 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | disclosed |