Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747582 | 0.91 | L3MBTL1 (0.37) | — | |
| SCHEMBL11741685 | 0.90 | MAPT (0.31) | — | |
| SCHEMBL11743524 | 0.89 | — | — | |
| SCHEMBL11749947 | 0.83 | NUDT1 (0.35) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11750097 | 0.81 | — | — | |
| SCHEMBL11746332 | 0.80 | — | — | |
| SCHEMBL11743305 | 0.78 | MAPT (0.34) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11750140 | 0.78 | MAPT (0.34) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11748846 | 0.77 | POLB (0.30) | — | |
| SCHEMBL11745628 | 0.76 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008232-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3979516-A | Anti-inflammatory 3-amino-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3948894-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |