Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 4/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117335 | 0.87 | ADRB2 (0.51) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL116508 | 0.81 | ADRB2 (0.46) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL29802253 | 0.79 | ADRB2 (0.57) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL10716822 | 0.77 | ADRB2 (0.55) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL116136 | 0.75 | ADRB2 (0.51) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL10627001 | 0.74 | ADRB2 (0.66) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL29492858 | 0.73 | ADRB2 (0.68) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL2844967 | 0.73 | ADRB2 (0.68) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL7599453 | 0.73 | ADRB2 (0.65) | ADRB2KCNH2KMT2ATOP2ATOP2B | |
| SCHEMBL114733 | 0.72 | ADRB2 (0.60) | ADRB2KCNH2KMT2ATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | ADRB2 702/4885KCNH2 1477/4885KMT2A 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.