Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512127 | 0.82 | ADRB1 (0.45) | CA2MEN1KMT2AADRB1CYP2D6 | |
| SCHEMBL11749742 | 0.77 | LMNA (0.54) | MEN1KMT2AADRB1CYP2D6KCNH2 | |
| SCHEMBL10970320 | 0.77 | ADRB2 (0.53) | ADRB1KCNH2ADRB2ADRB3 | |
| SCHEMBL11748971 | 0.77 | ADRB2 (0.64) | MEN1KMT2AADRB1CYP2D6KCNH2 | |
| SCHEMBL11751622 | 0.76 | ADRB2 (0.56) | MEN1KMT2AADRB1CYP2D6SLC6A2 | |
| SCHEMBL11237234 | 0.76 | CYP2D6 (0.71) | CA2MEN1HTTKMT2AADRB1 | |
| Hydrochloric Acid SCHEMBL11749004 | 0.76 | ADRB2 (0.55) | MEN1KMT2AADRB1CYP2D6ADRB2 | |
| SCHEMBL21950993 | 0.75 | CA9 (0.59) | CA2MEN1KMT2ACYP2D6CA12 | |
| SCHEMBL28669393 | 0.74 | MEN1 (0.47) | CA2MEN1HTTKMT2AADRB1 | |
| SCHEMBL11751396 | 0.74 | MEN1 (0.47) | CA2MEN1HTTKMT2AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056626-A | ADRENERGIC BLOCKING AGENTS | KAKENYAKU KAKO CO., LTD. (JA) | 1977-11-01 | — | — | US | claimed |
| US-4056626-A | ADRENERGIC BLOCKING AGENTS | KAKENYAKU KAKO CO., LTD. (JA) | 1977-11-01 | — | — | US | disclosed |