Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11749004 | 0.99 | ADRB2 (0.55) | ADRB2ADRB1LMNATDP1CYP1A2 | |
| SCHEMBL11755136 | 0.86 | ADRB2 (0.51) | ADRB2ADRB1LMNATDP1CYP1A2 | |
| SCHEMBL11755128 | 0.86 | ADRB2 (0.51) | ADRB2ADRB1LMNATDP1CYP1A2 | |
| SCHEMBL20331211 | 0.83 | SMN1; SMN2 (0.49) | LMNAKDM4EGLA | |
| SCHEMBL20442585 | 0.83 | SMN1; SMN2 (0.49) | LMNAKDM4EGLA | |
| SCHEMBL10508007 | 0.83 | LMNA (0.49) | LMNAKDM4EGLA | |
| SCHEMBL20334181 | 0.82 | TAS1R3 (0.48) | ADRB2LMNATSHRKDM4EGLA | |
| SCHEMBL1388388 | 0.80 | ATM (0.60) | ADRB2ADRB1CYP1A2TSHRCYP3A4 | |
| SCHEMBL1388386 | 0.80 | ATM (0.60) | ADRB2ADRB1CYP1A2TSHRCYP3A4 | |
| SCHEMBL10967303 | 0.79 | LMNA (0.51) | ADRB2ADRB1LMNATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056626-A | ADRENERGIC BLOCKING AGENTS | KAKENYAKU KAKO CO., LTD. (JA) | 1977-11-01 | — | — | US | claimed |
| US-4056626-A | ADRENERGIC BLOCKING AGENTS | KAKENYAKU KAKO CO., LTD. (JA) | 1977-11-01 | — | — | US | disclosed |