SCHEMBL11748830

SCHEMBL11748830

C=CCc1ccccc1OC(C)Br

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 6/20 0.53
ADRA2A P08913 5/20 0.53
ADRA2B P18089 5/20 0.53
HTR1A P08908 4/20 0.53
KCNH2 Q12809 2/20 0.53
ADRB2 P07550 3/20 0.49
ADRB1 P08588 3/20 0.49
LMNA P02545 2/20 0.49
ADRB3 P13945 1/20 0.49
SLC6A2 P23975 1/20 0.49
BDKRB2 P30411 1/20 0.49
SLC6A4 P31645 1/20 0.49
ADRA1A P35348 1/20 0.49
HTR2B P41595 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
KDM4E B2RXH2 2/20 0.48
PMP22 Q01453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15209922 0.86 ADRA2C (0.56) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL1325928 0.83 ADRB2 (0.56) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL27722723 0.83 ADRA2C (0.53) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL6213473 0.83 ADRA2C (0.53) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL28617191 0.83 ADRA2C (0.53) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL10806759 0.81 ALDH1A1 (0.49) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL5607788 0.80 ADRA2C (0.51) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL9626061 0.79 ADRA2C (0.53) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL24809163 0.79 ADRA2C (0.49) ADRA2CADRA2AADRA2BHTR1AKCNH2
SCHEMBL28135361 0.79 ADRA2C (0.49) ADRA2CADRA2AADRA2BHTR1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101108326-A Linear alkyl phenol homogeneous polyoxyethylene ether acetic acid surfactant and preparation method and application thereof CHINESE ACAD TECH INST PHYSICS (CN) 2008-01-23 CN claimed
CN-101108326-A Linear alkyl phenol homogeneous polyoxyethylene ether acetic acid surfactant and preparation method and application thereof CHINESE ACAD TECH INST PHYSICS (CN) 2008-01-23 CN disclosed
US-4027028-A HYPOTENSIVE AGENTS SCIENCE UNION ET CIE (FR) 1977-05-31 US disclosed