SCHEMBL1325928

SCHEMBL1325928

C=CCc1ccccc1OC(C)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 6/20 0.56
ADRB1 P08588 5/20 0.56
ADRA2C P18825 4/20 0.56
HTR1A P08908 3/20 0.56
ADRB3 P13945 3/20 0.56
LMNA P02545 2/20 0.56
KCNH2 Q12809 2/20 0.56
SLC6A2 P23975 1/20 0.56
BDKRB2 P30411 1/20 0.56
SLC6A4 P31645 1/20 0.56
ADRA1A P35348 1/20 0.56
HTR2B P41595 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
TSHR P16473 1/20 0.56
NFKB1 P19838 1/20 0.56
ALDH1A1 P00352 1/20 0.55
KDM4E B2RXH2 1/20 0.55
PMP22 Q01453 1/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10993978 0.87 ADRB2 (0.51) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL15209922 0.86 ADRA2C (0.56) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL7918186 0.84 ADRB2 (0.51) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL10449494 0.83 ALDH1A1 (0.52) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL28617191 0.83 ADRA2C (0.53) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL27722723 0.83 ADRA2C (0.53) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL6213473 0.83 ADRA2C (0.53) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL11748830 0.83 ADRA2C (0.53) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL289123 0.81 KMT2A (0.55) ADRB2ADRB1ADRA2CHTR1AADRB3
SCHEMBL6932646 0.81 ADRB2 (0.54) ADRB2ADRB1ADRA2CHTR1AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846981-B2 1,1-di[(alkylphenoxy)ethoxy]cyclohexanes SOUTHERN LITHOPLATE, INC. (US) 2014-09-30 US claimed
US-20130197274-A1 1,1-DI[(ALKYLPHENOXY)ETHOXY]CYCLOHEXANES SOUTHERN LITHOPLATE, INC. 2013-08-01 US claimed
EP-0774957-B1 AQUEOUS FOAMABLE COMPOSITION TILLOTTS PHARMA AG (CH) 2001-10-31 EP claimed
US-5679574-A SOLVENT EXTRACTION IN THE PRESENCE OF A DRYING AGENT, FILTRATION, FORMATION OF AN AQUEOUS EMULSION AND COMPARISON OF TURBIDIMETRIC RESPONSE TO A STANDARD CURVE; EFFICIENCY ENSYS ENVIRONMENTAL PRODUCTS, INC. (US) 1997-10-21 US claimed
EP-0136727-B2 AROMATIC POLYAMIDE YARN IMPREGNATED WITH LUBRICATING PARTICLES, A PROCESS FOR THE MANUFACTURE OF SUCH A YARN, AND PACKING MATERIAL OR ROPE CONTAINING THIS YARN AKZO N.V. (NL) 1992-10-07 EP claimed
US-5133875-A System and method for treating wastewater containing industrial esters UNIVERSITY OF SOUTH FLORIDA IN BEHALF OF BOARD OF REGENTS OF THE STATE OF FLORIDA (US) 1992-07-28 US claimed
EP-0136727-B1 AROMATIC POLYAMIDE YARN IMPREGNATED WITH LUBRICATING PARTICLES, A PROCESS FOR THE MANUFACTURE OF SUCH A YARN, AND PACKING MATERIAL OR ROPE CONTAINING THIS YARN AKZO N.V. (NL) 1987-08-12 EP claimed
EP-0136727-A1 Aromatic polyamide yarn impregnated with lubricating particles, a process for the manufacture of such a yarn, and packing material or rope containing this yarn AKZO N.V. (NL) 1985-04-10 EP claimed
EP-3038992-B1 NOVEL FIBERS, METHODS FOR THEIR PREPARATION AND USE IN THE MANUFACTURE OF REINFORCED ELEMENTS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2019-10-30 EP disclosed
EP-2473462-B1 HARDENING ACCELERATOR COMPOSITION CONTAINING PHOSPHATED POLYCONDENSATES CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2019-10-16 EP disclosed
EP-2882696-B1 PROCESS FOR PREPARING A HARDENING ACCELERATOR COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2019-04-10 EP disclosed
EP-2321235-B1 USE OF A PLASTICIZER-CONTAINING HARDENING ACCELERATOR COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2019-03-20 EP disclosed
EP-2664596-B1 Process for preparing a plasticizer-containing hardening accelerator composition CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2018-11-21 EP disclosed
EP-2664595-B1 PROCESS FOR PREPARING A PLASTICIZER-CONTAINING HARDENING ACCELERATOR COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2018-11-21 EP disclosed
US-4209532-A Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof UNION CARBIDE CORPORATION (US) 1980-06-24 US disclosed
US-4165318-A AGAINST CHEMICAL DECOMPOSITION OF THE 3-ISOTHIAZOLONE MILDEW CONTROLLING AGENT ROHM AND HAAS COMPANY (US) 1979-08-21 US disclosed
US-4129448-A A 3-ISOTHIAZOLONE ROHM AND HAAS COMPANY (US) 1978-12-12 US disclosed
US-4104043-A Esters of 3-hydroxyindone compounds as herbicides and miticides UNION CARBIDE CORPORATION (US) 1978-08-01 US disclosed
US-4091006-A MITICIDES AND HERBICIDES UNION CARBIDE CORPORATION (US) 1978-05-23 US disclosed
US-4031055-A ISOTHIAZOLONE; MILDEW RESISTANCE ROHM AND HAAS COMPANY (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197274-A1 1,1-DI[(ALKYLPHENOXY)ETHOXY]CYCLOHEXANES KHK, DEGS1, AKR1A1 ADRB2 1067/4885ADRB1 410/4885ADRA2C 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.