Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.61 |
| ▸ | CA2 | P00918 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744050 | 0.89 | SMN1; SMN2 (0.64) | CA1CA2NPC1RAB9AMAOA | |
| SCHEMBL4958360 | 0.78 | KDM4E (0.62) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL4953370 | 0.78 | KDM4E (0.58) | CA1CA2NPC1RAB9AKDM4E | |
| SCHEMBL3661536 | 0.77 | NPC1 (0.83) | CA1CA2NPC1RAB9AMAOA | |
| SCHEMBL5111031 | 0.76 | ALDH1A1 (0.58) | CA1CA2NPC1RAB9AMAOA | |
| SCHEMBL13699674 | 0.75 | KDM4E (0.59) | CA1CA2NPC1RAB9AKDM4E | |
| SCHEMBL8827792 | 0.75 | KDM4E (0.78) | CA1CA2NPC1RAB9AKDM4E | |
| SCHEMBL11750821 | 0.75 | CA1 (0.61) | CA1CA2NPC1RAB9AMAOA | |
| SCHEMBL17037021 | 0.75 | NPC1 (0.69) | CA1CA2NPC1RAB9AMAOA | |
| SCHEMBL11568180 | 0.75 | MAPK1 (0.57) | CA1CA2NPC1RAB9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932466-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1976-01-13 | — | — | US | claimed |
| US-4024160-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
| US-3932466-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1976-01-13 | — | — | US | disclosed |