Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751709 | 0.83 | PDGFRA (0.49) | PDGFRACDK5TYRO3KMOGUCY1A1 | |
| SCHEMBL11752415 | 0.81 | PDGFRA (0.42) | PDGFRACDK5TYRO3ALDH1A1LMNA | |
| SCHEMBL11749575 | 0.80 | PDGFRA (0.49) | PDGFRACDK5TYRO3KMOGAA | |
| SCHEMBL11751308 | 0.78 | ADORA2A (0.49) | PDGFRACDK5TYRO3KMOKMT2A | |
| SCHEMBL6480204 | 0.77 | PDGFRA (0.46) | PDGFRACDK5TYRO3KMOKMT2A | |
| SCHEMBL11750923 | 0.73 | ALDH1A1 (0.47) | PDGFRACDK5TYRO3KMOKMT2A | |
| SCHEMBL11745980 | 0.72 | THRB (0.43) | KMT2AALDH1A1MEN1LMNARAB9A | |
| SCHEMBL10320957 | 0.72 | NR4A2 (0.42) | KMOALDH1A1SMN1; SMN2ADORA2AMAT2A | |
| SCHEMBL12593994 | 0.71 | KMO (0.49) | KMOGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL31032598 | 0.69 | PLA2G4A (0.39) | PDGFRACDK5TYRO3KMOPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |