Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.63 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 3/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355557 | 0.91 | ADORA2B (0.67) | ADORA2BBLMGLAADORA2AACHE | |
| Bisdionin B SCHEMBL29896692 | 0.90 | ADORA2B (0.74) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL7384278 | 0.89 | ADORA2B (0.68) | ADORA2BBLMGLAADORA2AACHE | |
| Bisdionin C SCHEMBL10018600 | 0.87 | CHIT1 (0.75) | ADORA2BBLMGLAADORA2AACHE | |
| Bisdionin D SCHEMBL16120988 | 0.87 | ADORA2B (0.79) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL315740 | 0.86 | ADORA2B (0.82) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL16120981 | 0.86 | ADORA2B (0.77) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL10018599 | 0.85 | ADORA2B (0.72) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL25297970 | 0.84 | ADORA2B (0.67) | ADORA2BBLMGLAADORA2AACHE | |
| SCHEMBL7384282 | 0.84 | ADORA2B (0.69) | ADORA2BBLMGLAADORA2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912598-B | Nucleoside derivative for preventing and treating inflammatory reaction and application thereof | 四川大学华西医院 | 2022-09-13 | — | — | CN | disclosed |
| WO-2020192665-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | 四川大学华西医院 | 2020-10-01 | — | — | WO | disclosed |
| CN-109912598-A | Nucleoside derivate and its application for preventing and treating inflammatory reaction | 四川大学华西医院 | 2019-06-21 | — | — | CN | disclosed |
| US-4060618-A | Quaternary xanthinylalkyl nortropine | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-11-29 | — | — | US | disclosed |