SCHEMBL117548

SCHEMBL117548

CCc1cc(Cc2ccc(N)c(C(C)C)c2)cc(CC)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.45
ALDH1A1 P00352 3/20 0.38
POLB P06746 2/20 0.38
HTT P42858 1/20 0.38
GAA P10253 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
CYP3A4 P08684 1/20 0.37
MEN1 O00255 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
CDC25B P30305 1/20 0.37
CASP6 P55212 1/20 0.37
RCE1 Q9Y256 1/20 0.37
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DHFR P00374 2/20 0.35
THRA P10827 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3942470 0.90 THRB (0.47) THRBALDH1A1POLBGAAKDM4E
SCHEMBL9812330 0.88 THRB (0.40) THRBALDH1A1POLBGAAKDM4E
SCHEMBL3943098 0.85 THRB (0.47) THRBALDH1A1POLBGAAKDM4E
SCHEMBL292418 0.85 POLB (0.39) POLBHTTDHFR
SCHEMBL24622936 0.85 POLB (0.39) POLBHTTDHFR
SCHEMBL100769 0.85 THRB (0.51) THRBALDH1A1POLBGAAKDM4E
SCHEMBL29942793 0.85 THRB (0.51) THRBALDH1A1POLBGAAKDM4E
Ammonia Solution, Strong SCHEMBL11024542 0.83 POLB (0.38) POLBHTTDHFR
SCHEMBL3935601 0.83 ALDH1A1 (0.44) ALDH1A1POLBHTTGAAKDM4E
SCHEMBL433294 0.83 DHFR (0.39) POLBHTTDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240343941-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-10-17 US disclosed
EP-4380990-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-06-12 EP disclosed
CN-117836344-A Dual cure resin composition comprising uretdione containing compounds and use thereof in 3D printing 巴斯夫欧洲公司 2024-04-05 CN disclosed
WO-2023012000-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2023-02-09 WO disclosed
CN-112384545-B Elastomeric polyurethane foams and process for producing the same 巴斯夫欧洲公司 2023-01-24 CN disclosed
US-20220340704-A1 SPRAY POLYURETHANE ELASTOMERS AND METHODS FOR PRODUCING THE SAME BASF SE (DE) 2022-10-27 US disclosed
EP-4038126-A1 SPRAY POLYURETHANE ELASTOMERS AND METHODS FOR PRODUCING THE SAME BASF SE (DE) 2022-08-10 EP disclosed
CN-114555672-A Spray-coated polyurethane elastomer and production method thereof 巴斯夫欧洲公司 2022-05-27 CN disclosed
EP-3818094-A1 ELASTOMERIC POLYURETHANE FOAMS AND METHODS FOR PRODUCING THE SAME BASF SE (DE) 2021-05-12 EP disclosed
WO-2021067344-A1 SPRAY POLYURETHANE ELASTOMERS AND METHODS FOR PRODUCING THE SAME BASF SE (DE) 2021-04-08 WO disclosed
US-20070024973-A1 Method of manufacturing a high impact polarized optical element and polarized optical element including an integrally bonded polarizing film BARBERINI S.P.A. (IT) 2007-02-01 US disclosed
US-6562932-B1 Optically clear, light-stable polyurethane-urea elastomer having an onset softening point of at least 130 degrees C., processed at ambient temperature and casted in a mold at an isocyanate index of 95 to 120. BAYER CORPORATION 2003-05-13 US disclosed
EP-1302491-A1 Light stable one-shot urethane-urea elastomers Bayer Corporation (US) 2003-04-16 EP disclosed
US-6530849-B2 Copolymer of toluene-2,4- or 2,6-diisocyanate, low molecular weight polyoxypropylene glycol and diamine functional chain extender; high resilience and shear resistance UNIROYAL CHEMICAL COMPANY, INC. 2003-03-11 US disclosed
US-20020049099-A1 Low cost, resilient, shear resistant polyurethane elastomers for golf ball covers UNIROYAL CHEMICAL COMPANY, INC. 2002-04-25 US disclosed
US-6309313-B1 AN INEXPENSIVE COVER OF A POLYETHERURETHANE COPOLYMER CHAIN EXTENDED BY A DIAMINE OR DIHYDROXY COMPOUND; POLYETHER MONOMER COMPRISING ETHYLENE GLYCOL OR ETHYLENE GLYCOL AND PROPYLENE GLYCOL; COLORFASTNESS; PHOTOSTABILITY UNIROYAL CHEMICAL COMPANY, INC. 2001-10-30 US disclosed
US-6174984-B1 Clear, resilient polyurethane elastomers UNIROYAL CHEMICAL COMPANY, INC. 2001-01-16 US disclosed
WO-2000077062-A1 CLEAR, RESILIENT POLYURETHANE ELASTOMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-12-21 WO disclosed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed