Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755128 | 1.00 | ADRB2 (0.51) | ADRB2ADRB1PTGS1SLC6A2LMNA | |
| SCHEMBL11751622 | 0.86 | ADRB2 (0.56) | ADRB2ADRB1PTGS1SLC6A2LMNA | |
| Hydrochloric Acid SCHEMBL11749004 | 0.85 | ADRB2 (0.55) | ADRB2ADRB1LMNATDP1CNR1 | |
| SCHEMBL11751418 | 0.78 | ADRB2 (0.54) | ADRB2ADRB1PTGS1SLC6A2LMNA | |
| SCHEMBL11751687 | 0.78 | ADRB2 (0.54) | ADRB2ADRB1PTGS1SLC6A2LMNA | |
| SCHEMBL11751680 | 0.78 | ADRB2 (0.54) | ADRB2ADRB1PTGS1SLC6A2LMNA | |
| SCHEMBL11751411 | 0.78 | ADRB2 (0.54) | ADRB2ADRB1PTGS1SLC6A2LMNA | |
| SCHEMBL11748309 | 0.76 | ADRB1 (0.43) | ADRB2ADRB1LMNATDP1CNR1 | |
| SCHEMBL28413318 | 0.75 | ADRB2 (0.60) | ADRB2ADRB1PTGS1SLC6A2MAPT | |
| SCHEMBL20552867 | 0.72 | ADRB2 (0.70) | ADRB2ADRB1PTGS1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056626-A | ADRENERGIC BLOCKING AGENTS | KAKENYAKU KAKO CO., LTD. (JA) | 1977-11-01 | — | — | US | disclosed |