Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831498 | 0.84 | POLB (0.56) | ALDH1A1NOTUMLMNASMN1; SMN2KDM4E | |
| SCHEMBL8018491 | 0.84 | MTNR1A (0.51) | MTNR1AACEPOLBL3MBTL1 | |
| SCHEMBL5740568 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1NOTUMLMNASMN1; SMN2KDM4E | |
| SCHEMBL5483115 | 0.80 | PDK1 (0.55) | ALDH1A1NOTUMLMNASMN1; SMN2KDM4E | |
| SCHEMBL2708840 | 0.79 | CETP (0.54) | NOTUMCETP | |
| SCHEMBL30716840 | 0.79 | CETP (0.54) | NOTUMCETP | |
| SCHEMBL15187564 | 0.75 | NOTUM (0.65) | ALDH1A1NOTUMLMNASMN1; SMN2KDM4E | |
| SCHEMBL8904624 | 0.75 | NOTUM (0.50) | MTNR1AALDH1A1NOTUMLMNAKMT2A | |
| SCHEMBL16585695 | 0.75 | PDK1 (0.60) | ALDH1A1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL3441638 | 0.75 | MTNR1A (0.43) | MTNR1AKMT2AACEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045578-A | N-CHLORO-AMINO ACID DERIVATIVES EXHIBITING ANTIBACTERIAL ACTIVITY | INTERX RESEARCH CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3966796-A | ANTIBACTERIAL ACTIVITY | INTERX RESEARCH CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |