Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441713 | 0.86 | ACE (0.47) | MTNR1AACEMTNR1B | |
| SCHEMBL7993369 | 0.84 | DRD2 (0.54) | ACE | |
| SCHEMBL11756352 | 0.84 | MTNR1A (0.48) | MTNR1AACEPOLBL3MBTL1 | |
| SCHEMBL2288109 | 0.80 | TSHR (0.63) | POLBTSHR | |
| SCHEMBL20462833 | 0.80 | TSHR (0.62) | ACEPOLBL3MBTL1TSHRPDK1 | |
| SCHEMBL28345381 | 0.78 | ACE (0.47) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL28068692 | 0.78 | ACE (0.47) | ACETSHRPDK1PDK2PDK3 | |
| SCHEMBL29278844 | 0.77 | NOTUM (0.49) | — | |
| SCHEMBL7005115 | 0.77 | ACE (0.41) | MTNR1AACETSHRPDK1PDK2 | |
| SCHEMBL22298024 | 0.76 | MTNR1A (0.61) | MTNR1APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6099625-A | Ink composition | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
| EP-0823927-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034916-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1996-11-07 | — | — | WO | disclosed |