Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28179746 | 0.84 | SLC22A12 (0.49) | SLC22A12PTGS2MAPK1CNR1KDM4E | |
| SCHEMBL28009339 | 0.82 | SLC22A12 (0.47) | SLC22A12PTGS2MAPK1CNR1KDM4E | |
| SCHEMBL460510 | 0.82 | ALOX15 (0.50) | SLC22A12PTGS2MAPK1KDM4ELMNA | |
| SCHEMBL27664892 | 0.82 | ALOX15 (0.50) | SLC22A12PTGS2MAPK1KDM4ELMNA | |
| SCHEMBL30021764 | 0.79 | ALOX15 (0.48) | SLC22A12PTGS2MAPK1KDM4ELMNA | |
| Biphenyl SCHEMBL1029706 | 0.79 | LMNA (0.58) | MAPK1KDM4ELMNAL3MBTL1MMP12 | |
| Biphenyl SCHEMBL6525433 | 0.79 | LMNA (0.58) | MAPK1KDM4ELMNAL3MBTL1MMP12 | |
| Hydrochloric Acid SCHEMBL4703144 | 0.79 | ALOX15 (0.48) | SLC22A12PTGS2MAPK1KDM4ELMNA | |
| SCHEMBL5157937 | 0.79 | CNR1 (0.55) | SLC22A12MAPK1CNR1POLBLMNA | |
| SCHEMBL14525924 | 0.77 | ALDH1A1 (0.50) | SLC22A12PTGS2HSD17B10MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046763-A | INTERMEDIATE FOR ULTRAVIOLET LIGHT ABSORBERS | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |