SCHEMBL11758993

SCHEMBL11758993

CCCSP(=O)(OCC)Oc1ccc(Sc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.44
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11033364 0.94 CA1 (0.37) ACHE
SCHEMBL11757007 0.92 KCNH2 (0.42) KCNH2
SCHEMBL11761760 0.91 CA12 (0.46) KCNH2
SCHEMBL11756201 0.90 CA12 (0.40) KCNH2
SCHEMBL117138 0.89 L3MBTL1 (0.47) ACHE
SCHEMBL5933991 0.88 MEN1 (0.41)
SCHEMBL11866713 0.86 LTA4H (0.44) ACHE
SCHEMBL9009188 0.85 CA1 (0.37) ACHE
SCHEMBL11757852 0.84 ALDH1A1 (0.43) KCNH2ACHE
SCHEMBL11753622 0.84 MTNR1A (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029774-A PHOSPHORODITHIOATES AND THEIR DERIVATIVES AND PESTICIDAL USE ROHM AND HAAS COMPANY (US) 1977-06-14 US disclosed