SCHEMBL90533

SCHEMBL90533

CN(C)c1ccc(N=O)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 13/20 0.50
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 3/20 0.48
THRB P10828 3/20 0.48
MAPK1 P28482 2/20 0.48
HIF1A Q16665 2/20 0.48
KDM4E B2RXH2 2/20 0.48
HPGD P15428 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
RGS12 O14924 1/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
ALOX15 P16050 1/20 0.48
NFKB1 P19838 1/20 0.48
APEX1 P27695 1/20 0.48
BRCA1 P38398 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29914719 1.00 KCNH2 (0.50) KCNH2ALDH1A1HSD17B10THRBMAPK1
Hydrochloric Acid SCHEMBL104308 0.98 KCNH2 (0.51) KCNH2ALDH1A1HSD17B10THRBMAPK1
SCHEMBL3856198 0.98 KCNH2 (0.49) KCNH2ALDH1A1HSD17B10THRBMAPK1
SCHEMBL11759545 0.83 KCNH2 (0.66) KCNH2ALDH1A1HSD17B10THRBMAPK1
SCHEMBL11759552 0.83 KCNH2 (0.66) KCNH2ALDH1A1HSD17B10THRBMAPK1
SCHEMBL374911 0.79 MAPT (0.53) ALDH1A1THRBMAPK1KDM4EHPGD
SCHEMBL29740108 0.79 MAPT (0.53) ALDH1A1THRBMAPK1KDM4EHPGD
Hydrochloric Acid SCHEMBL103959 0.78 MAPT (0.51) ALDH1A1THRBMAPK1KDM4EHPGD
SCHEMBL145777 0.78 ALDH1A1 (0.48) ALDH1A1HSD17B10THRBMAPK1HIF1A
SCHEMBL144585 0.76 ALDH1A1 (0.47) KCNH2ALDH1A1HSD17B10THRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP claimed
JP-1052783-A None JP disclosed
US-12605468-B2 Oxazine-based fluorophore compounds for nerve-specific imaging OREGON HEALTH & SCIENCE UNIVERSITY (US) 2026-04-21 US disclosed
US-12011433-B2 Mofezolac derivatives as multi-functions selective COX-1 inhibitors ITEL TELECOMUNICAZIONI S.R.L. (IT) 2024-06-18 US disclosed
EP-3782990-B1 MOFEZOLAC DERIVATIVE AS IMAGING AGENT IN A DIAGNOSTIC METHOD OF CANCER UNIV DEGLI STUDI DI BARI ALDO MORO (IT) 2023-06-07 EP disclosed
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-05-11 US disclosed
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2023-05-11 US disclosed
EP-4093443-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING Oregon Health & Science University (US) 2022-11-30 EP disclosed
US-11492359-B2 Near-infrared nerve-sparing fluorophores OREGON HEALTH & SCIENCE UNIVERSITY (US) 2022-11-08 US disclosed
CN-115279423-A Oxazine-based fluorophore compounds for neurospecific imaging 俄勒冈健康与科学大学 2022-11-01 CN disclosed
US-5847071-A Photosensitive resin composition HITACHI, CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed
US-5844066-A Process for the preparation of lactic acid-based polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-12-01 US disclosed
WO-1998003497-A1 COVALENTLY IMMOBILISED FLUOROIONOPHORES FOR OPTICAL ION SENSORS NOVARTIS AG (CH) 1998-01-29 WO disclosed
US-5686540-A Process for the preparation of lactic acid-based polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-11-11 US disclosed
US-5668248-A POLYAMIC ACID ESTERS HITACHI CHEMICAL CO., LTD. (JP) 1997-09-16 US disclosed
EP-0765913-A1 Process for the preparation of lactic acid-based polyester compositions DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-04-02 EP disclosed
US-5472823-A Polyamic acids HITACHI CHEMICAL CO., LTD. (JP) 1995-12-05 US disclosed
US-5318882-A Nitrosodiphenylamine compounds render dyes lightfast TAIYO YUDEN CO., LTD. (JP) 1994-06-07 US disclosed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP disclosed
JP-S6452783-A NOVEL SPIROBENZOXAZINE COMPOUND TORAY INDUSTRIES 1989-02-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492359-B2 Near-infrared nerve-sparing fluorophores NTRK1, PMP22, GAP43 KCNH2 195/4885ALDH1A1 813/4885HSD17B10 1810/4885
US-20230148317-A1 OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING GAP43, NTRK1, CHAT KCNH2 530/4885ALDH1A1 1300/4885HSD17B10 2874/4885
US-12605468-B2 Oxazine-based fluorophore compounds for nerve-specific imaging CHRNB2, CHRNB3, CHRNB4 KCNH2 204/4885ALDH1A1 1339/4885HSD17B10 2385/4885
US-12011433-B2 Mofezolac derivatives as multi-functions selective COX-1 inhibitors PTGS1, HMOX1, HMGB1 KCNH2 4242/4885ALDH1A1 648/4885HSD17B10 3127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.