Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90533 | 1.00 | KCNH2 (0.50) | KCNH2ALDH1A1HSD17B10THRBMAPK1 | |
| Hydrochloric Acid SCHEMBL104308 | 0.98 | KCNH2 (0.51) | KCNH2ALDH1A1HSD17B10THRBMAPK1 | |
| SCHEMBL3856198 | 0.98 | KCNH2 (0.49) | KCNH2ALDH1A1HSD17B10THRBMAPK1 | |
| SCHEMBL11759545 | 0.83 | KCNH2 (0.66) | KCNH2ALDH1A1HSD17B10THRBMAPK1 | |
| SCHEMBL11759552 | 0.83 | KCNH2 (0.66) | KCNH2ALDH1A1HSD17B10THRBMAPK1 | |
| SCHEMBL374911 | 0.79 | MAPT (0.53) | ALDH1A1THRBMAPK1KDM4EHPGD | |
| SCHEMBL29740108 | 0.79 | MAPT (0.53) | ALDH1A1THRBMAPK1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL103959 | 0.78 | MAPT (0.51) | ALDH1A1THRBMAPK1KDM4EHPGD | |
| SCHEMBL145777 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HSD17B10THRBMAPK1HIF1A | |
| SCHEMBL144585 | 0.76 | ALDH1A1 (0.47) | KCNH2ALDH1A1HSD17B10THRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279423-A | Oxazine-based fluorophore compounds for neurospecific imaging | 俄勒冈健康与科学大学 | 2022-11-01 | — | — | CN | disclosed |